separate instances of Thunderbird or Kmail

[Gordon Schulz]

On Wed, 30 Jul 2008 12:57, O. Sinclair <o.sinclair at gmail.com> wrote:

[...]
> So I am looking for a way to run a second instance of Thunderbird or 
> Kmail that is totally separate and "unaware" of the "main" ones. 
[...]

Am I missing an obvious point here or isn't that easily done changing
Profiles in Thunderbird and/or KMail?
-- 
Gordon.